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Among the animals and plants with which we share our planet, there is inevitable senescence. In recent years, however, a building revolution in the science of gerontology has heralded the possibility of life extension.


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The flip side is pife mortality in this country continues to bump right up against percent. A dark side to human nature has long created a range of problems with negative or even tragic consequences.

At the time, high cost limited the supply of the machines, but even those who did have access to one could often not afford the treatment. Instead, aging appears to be the gradual accumulation of cellular damage wjo by the byproducts of the biochemistry of life itself. Related Content. As Appleyard points out, the best guide to imagining what the world would become with people living greatly extended lives is simply to look at the world that our human nature has generated in the past.

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By the time we can make the normal life span, new innovations will extend it toand so on, effectively leapfrogging expected life span to, well, no end in sight. Rather, just as transfusions and transplants, pacemakers and statin drugs have extended life today—and sanitation, clean water and food, and an application of the germ theory of disease extended human life in an earlier time—so another new age of medicine is on the horizon.

A microscopic worm may experience a timeline of merely a few days before it literally grows old and dies; for a tortoise or a large fish, the life calendar seems open-ended. The first inherent assumption is that innovative medical techniques would be available for all.

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This is not to suggest that science is on the cusp of developing the ultimate silver bullet against aging. However, it seems unlikely that man will save his own soul. As our llife of the biochemistry of aging increases exponentially, it is no surprise that around the globe scientists are lkve hopeful paths that will provide ways to increase human longevity.

Our clock is set somewhere in between. Indeed, if we are hoping not just for temporary life extension but for immortality in a peaceful world that can sustain life for eternity, then however we look to achieve it, whatever system or entity we put our confidence in, wanrs is required. And who would want to live indefinitely if it meant continued existence as an economic slave, or living under an oppressive and brutal dictatorship or in a war-ravaged and violence-filled country?

In recent years, however, a building revolution in the science of gerontology has heralded the possibility of life extension. Immortal life will be won by applied knowledge. Considering the real-life track record, this does not seem likely.

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Meanwhile, biotechnology companies are seeking to bring new products to market—drugs, cells, tissues, and procedures—which they, too, hope will go some way toward extending life as well as bring a profit. Around the world, health-care authorities run a de facto rationing system based on cost-benefit analysis. Kenyon studies soil worms called nematodes and the genetics of aging. This is leading some to speculate about just what the limits to human life might be; adding another decade or two or even centuries might be possible.

Undoubtedly there will be new breakthroughs, making new headlines, giving rise to new hopes.

We are more likely simply to embed our failings and prejudices in the new model. This disparity becomes even greater when we cast our eyes globally. Among the animals and plants with which we share our planet, there is inevitable senescence.

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More of the Same In addition to his own concerns about the sustainability and equitable distribution of resources in a scenario of successful life extension, Appleyard questions the long-term motivational factor, love of self. It would be shortsighted indeed to disregard the possibility of amazing breakthroughs in medical treatments, but when we consider the complexity of the aging process and of age-related diseases, we have to acknowledge that any single approach offers but limited hope of tackling dants multifaceted phenomenon that we do not fully understand at present.

Jay Olshansky and Bruce A. This will require further identification of the links between specific genes, their cell maintenance functions, and other interactions between cells, the body, and the environment. The modern view of aging is being decoupled from calendar time.

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In still unknown interrelationships, the metabolic reactions of the living process operate to create a sort of species-specific shelf-life. Other inequalities also exist.

Man will save his own soul. If these genes also participate in critical developmental pathways early in life, then their elimination could have catastrophic consequences. Turning back the hands of cellular time and resetting them permanently in youthful self-repair mode is the greater goal in longevity research.

Once we move beyond our fatalistic view of lifespan, de Grey has faith that science will show us how to reprogram our bodies to maintain our cellular systems in a youthful, self-restorative state virtually forever. We will not suddenly have ways to challenge Methuselah.

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Unfortunately the supply of the particular species required is limited. For example, it may become possible to eliminate genes that are linked to the frailty, disability and disease associated with aging. Is more of the same what we really want?

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